HINT1 : histidine triad nucleotide binding protein 1
Description
HINT1, also known as histidine triad nucleotide-binding protein 1, is a ubiquitous gene encoding a protein that plays critical roles in various cellular processes, including signal transduction, cell growth, and apoptosis. It acts as a regulatory molecule involved in the hydrolysis of nucleotides, particularly NAD+ and NADP+, influencing cellular metabolism and signaling pathways. HINT1‘s diverse functions extend to its involvement in inflammatory responses, DNA repair, and the regulation of gene expression.
Associated Diseases
- Cancer (various types, including breast, colon, lung, and prostate cancers)
- Neurodegenerative disorders (Alzheimer‘s disease, Parkinson‘s disease)
- Inflammatory bowel disease
- Metabolic disorders (type 2 diabetes, obesity)
Did you know?
HINT1 gene expression is often dysregulated in various diseases, making it a potential target for therapeutic intervention.
