HIKESHI

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Description

HIKESHI, also known as C17orf53, is a gene that plays a critical role in the regulation of cell growth and proliferation. It encodes a protein that interacts with multiple signaling pathways, including the Wnt pathway, and is involved in the control of cell cycle progression. HIKESHI‘s function is particularly important in the context of development, where it contributes to the proper formation and development of organs and tissues. Dysregulation of HIKESHI expression or function has been linked to various diseases, highlighting its importance in maintaining cellular homeostasis.

Associated Diseases

• Cancer (specifically colorectal, lung, and breast cancers)
• Neurodevelopmental disorders
• Metabolic diseases

Did you know?

The name "HIKESHI" comes from the Japanese word for "fireman", reflecting the gene‘s role in controlling cell growth and proliferation, which are often associated with the rapid spread of "fire" in a population of cells.