HGF

Description

The HGF gene, encoding Hepatocyte Growth Factor, plays a critical role in tissue regeneration and repair. HGF is a powerful growth factor that promotes cell proliferation, migration, and survival, primarily in the liver, but also in various other organs. It acts through its receptor, c-Met, initiating intracellular signaling cascades that drive tissue remodeling and repair. HGF‘s functions are particularly important in wound healing, where it stimulates the growth and migration of fibroblasts and endothelial cells, leading to tissue regeneration. Additionally, HGF is involved in organ development, angiogenesis, and tumor suppression.

Associated Diseases

• Liver diseases, including cirrhosis and hepatitis
• Wound healing impairments
• Cancer, particularly in the liver, lung, and breast
• Cardiovascular diseases
• Neurological disorders

Did you know?

HGF‘s ability to promote tissue regeneration has led to its investigation as a potential therapeutic agent for various diseases, including liver failure and wound healing.