HFM1
Description
The HFM1 (helicase for meiosis 1) is a protein-coding gene located on chromosome 1.
The HFM1 gene encodes a protein crucial for homologous recombination of chromosomes in humans. Mutations in both copies of this gene (biallelic mutations) lead to recessive primary ovarian insufficiency.
The HFM1 gene is involved in the formation of crossovers and complete synapsis of homologous chromosomes during meiosis.
HFM1 is also known as MER3, POF9, SEC63D1, Si-11, Si-11-6, helicase.
