HEPACAM : hepatic and glial cell adhesion molecule
Description
HEPACAM, also known as Hepatic Cellular Adhesion Molecule, is a transmembrane protein crucial for liver development, regeneration, and homeostasis. It plays a vital role in cell-cell interactions, signaling pathways, and tissue organization within the liver. HEPACAM is involved in various cellular processes, including adhesion, migration, proliferation, and differentiation. Its expression is tightly regulated during liver development and can be altered in various liver diseases.
Associated Diseases
- Hepatocellular carcinoma (HCC)
- Liver fibrosis
- Non-alcoholic fatty liver disease (NAFLD)
- Liver cirrhosis
- Hepatitis
- Biliary atresia
Did you know?
HEPACAM has been found to be involved in the development of liver cancer, specifically HCC, where its expression is often upregulated and contributes to tumor growth and metastasis.
