GZF1
Description
GZF1, also known as GLIS1, is a zinc finger transcription factor that plays crucial roles in various developmental processes, particularly in the pancreas and nervous system. It is encoded by the GZF1 gene and functions by binding to specific DNA sequences, regulating the expression of target genes. GZF1‘s importance is highlighted by its involvement in various diseases, including diabetes, neurodevelopmental disorders, and cancer. Understanding the intricate mechanisms by which GZF1 exerts its influence is critical for unraveling the complexities of these diseases and developing effective therapeutic strategies.
Associated Diseases
- Diabetes Mellitus
- Neurodevelopmental Disorders (e.g., intellectual disability, autism spectrum disorder)
- Pancreatic Cancer
- Other Cancers
Did you know?
GZF1 mutations have been linked to a rare genetic disorder called GLIS1 syndrome, characterized by severe diabetes, developmental delays, and other abnormalities.
