GPR68

Description

GPR68, also known as the G protein-coupled receptor 68, is a transmembrane protein that plays a crucial role in regulating various metabolic processes. It belongs to the family of G protein-coupled receptors, which are involved in signal transduction pathways. GPR68 is primarily expressed in the brain, pancreas, and adipose tissue, where it interacts with various ligands, including lipids and hormones. Its activation triggers downstream signaling cascades that influence glucose homeostasis, insulin sensitivity, and lipid metabolism. Understanding the function of GPR68 is essential for developing therapeutic strategies targeting metabolic disorders and other related diseases.

Associated Diseases

• Type 2 Diabetes
• Obesity
• Non-alcoholic fatty liver disease (NAFLD)
• Metabolic syndrome
• Cardiovascular disease

Did you know?

GPR68 is highly expressed in the hypothalamus, a brain region involved in regulating appetite and energy expenditure. This suggests a potential role of GPR68 in controlling food intake and body weight.