GLRX5
Description
GLRX5, also known as glutaredoxin 5, is a gene that encodes a protein crucial for maintaining cellular redox balance. This protein acts as a reductase, utilizing glutathione to reduce disulfide bonds in other proteins, thereby regulating their activity and protecting cells from oxidative stress. The GLRX5 gene plays a vital role in various cellular processes, including protein folding, DNA repair, and signal transduction. Its dysregulation has been linked to several diseases.
Associated Diseases
- Cancer (various types)
- Neurodegenerative disorders (Alzheimer‘s disease, Parkinson‘s disease)
- Cardiovascular diseases
- Diabetes
Did you know?
GLRX5 is highly expressed in the brain, suggesting a crucial role in neuronal function and protection against oxidative damage.