GGT1
Description
The GGT1 gene, provides instructions for making gamma-glutamyltransferase (GGT), an enzyme crucial for glutathione metabolism. Glutathione, a powerful antioxidant, plays a vital role in protecting cells from damage caused by free radicals. GGT catalyzes the transfer of a gamma-glutamyl group from glutathione to other molecules, which can facilitate glutathione recycling and detoxification processes. The GGT1 gene is expressed in various tissues, including the liver, kidneys, and intestines, where it contributes to maintaining cellular homeostasis and overall health.
Associated Diseases
- Liver disease (e.g., alcoholic liver disease, non-alcoholic fatty liver disease)
- Cancer (e.g., colorectal cancer, pancreatic cancer)
- Diabetes
- Cardiovascular disease
- Kidney disease
- Neurodegenerative disorders
Did you know?
GGT levels in the blood can be used as a marker for liver damage and other health conditions.