GAN : gigaxonin

Description

The GAN gene, encodes a protein called GAN, which plays a crucial role in cellular growth and development. GAN is involved in the regulation of cell cycle progression, DNA replication, and DNA repair. Mutations in the GAN gene can disrupt these vital processes, leading to various developmental disorders and cancers. This article delves into the intricacies of the GAN gene, its associated diseases, and ongoing research aimed at understanding and treating these conditions.

Associated Diseases

• Microcephalic Osteodysplastic Primordial Dwarfism Type II (MOPD II)
• Cerebro-oculo-facio-skeletal syndrome (COFS)
• Cancer (specifically colorectal, lung, and breast cancer)
• Intellectual Disability
• Developmental Delays

Did you know?

Mutations in the GAN gene can cause a rare genetic disorder called MOPD II, characterized by severe dwarfism, microcephaly, and other developmental abnormalities.