FUS : FUS RNA binding protein

Description

The FUS gene encodes a protein known as fused in sarcoma (FUS). This protein plays a crucial role in various cellular processes, including RNA splicing, transcription, and DNA repair. FUS is found in the nucleus of cells and interacts with a wide range of RNA and DNA molecules. Mutations in the FUS gene are linked to several neurodegenerative diseases, most notably amyotrophic lateral sclerosis (ALS). Understanding the intricate functions of FUS and its involvement in disease pathogenesis is essential for developing effective therapeutic strategies.

Associated Diseases

• Amyotrophic Lateral Sclerosis (ALS)
• Frontotemporal Dementia (FTD)
• Prostate Cancer
• Ovarian Cancer
• Breast Cancer

Did you know?

FUS protein has a unique ability to switch between liquid and solid states within the cell, a process known as phase separation. This property is believed to be crucial for its diverse functions in RNA and DNA metabolism.