FOXN1 : forkhead box N1

Description

The FOXN1 gene plays a crucial role in the development and function of the thymus, a vital organ for the immune system. It encodes a transcription factor, FOXN1 protein, which regulates the expression of numerous genes essential for T cell maturation and immune response. Mutations in FOXN1 can lead to severe immunodeficiency disorders, highlighting its importance in maintaining a healthy immune system.

Associated Diseases

• Severe Combined Immunodeficiency (SCID)
• Ataxia-Telangiectasia-Like Disorder (ATLD)
• Bare Lymphocyte Syndrome (BLS)
• Thymic Hypoplasia
• Immune Dysregulation

Did you know?

The FOXN1 gene is highly conserved across various species, emphasizing its fundamental role in immune system development.