FGB

Description

The FGB gene provides instructions for making fibrinogen, a protein essential for blood clotting. Fibrinogen is a key component of the coagulation cascade, a complex series of events that stops bleeding. When a blood vessel is damaged, fibrinogen is converted into fibrin, which forms a mesh-like network that traps blood cells and platelets, forming a clot. This process is crucial for preventing excessive blood loss.

Associated Diseases

• Congenital afibrinogenemia: A rare genetic disorder characterized by the absence of fibrinogen in the blood, leading to severe bleeding problems.
• Dysfibrinogenemia: A condition where the fibrinogen protein is abnormal, leading to impaired blood clotting.
• Thrombosis: Abnormal blood clotting, potentially caused by increased fibrinogen levels.
• Liver disease: Liver damage can affect fibrinogen production, leading to clotting problems.
• Premature birth: Premature infants often have low fibrinogen levels, increasing the risk of bleeding.

Did you know?

Fibrinogen levels are naturally higher during pregnancy to prepare for potential blood loss during childbirth.