FGA : fibrinogen alpha chain

Description

The FGA gene, provides instructions for creating the alpha chain of fibrinogen, a crucial protein involved in blood clotting. Fibrinogen, a large protein produced by the liver, circulates in the blood and converts into fibrin, forming a mesh-like structure that traps blood cells and platelets, ultimately forming a clot. The FGA gene, alongside FGB and FGG genes, encodes the three different polypeptide chains that make up the fibrinogen molecule. Variations in the FGA gene can influence fibrinogen levels and blood clotting ability.

Associated Diseases

• Thrombophilia (Increased Risk of Blood Clots)
• Bleeding Disorders (Reduced Clotting Ability)
• Congenital Fibrinogen Deficiency
• Cardiovascular Disease

Did you know?

Fibrinogen is the most abundant clotting factor in blood and its levels can be measured using a simple blood test.