FBXO31

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Description

FBXO31, also known as F-box protein 31, is a gene that encodes a protein involved in a variety of cellular functions, including protein degradation, cell cycle regulation, and DNA damage response. It acts as a substrate recognition component of the SCF (Skp1-Cul1-F-box) ubiquitin ligase complex, targeting specific proteins for ubiquitination and subsequent degradation by the proteasome. This intricate process plays a crucial role in maintaining cellular homeostasis and responding to various stimuli. FBXO31‘s involvement in diverse cellular pathways suggests its potential role in human health and disease.

Associated Diseases

• Cancer (e.g., colorectal cancer, breast cancer)
• Neurological disorders (e.g., Alzheimer‘s disease, Parkinson‘s disease)
• Immune system disorders

Did you know?

FBXO31 expression levels have been found to be altered in various cancer types, suggesting its potential as a diagnostic or prognostic biomarker.