FAS : Fas cell surface death receptor

FAS: The Master Regulator of Cell Death

Description

The Fas gene (also known as TNFSF6) holds the blueprints for a critical protein that orchestrates the intricate process of cell signaling. This protein assembles into trimers, which are three-member complexes that interact with specific molecules to trigger a chain of events crucial for maintaining tissue homeostasis.

Associated Diseases

Dysregulation of FAS signaling is implicated in a range of autoimmune conditions, including:

• Type 1 diabetes
• Rheumatoid arthritis
• Systemic lupus erythematosus

Did you Know ?

Defects in the FAS gene can lead to an increased susceptibility to certain types of cancer. For instance, individuals with FAS mutations are more prone to developing Hodgkin‘s lymphoma.