FARSB


Description

The FARSB (phenylalanyl-tRNA synthetase subunit beta) is a protein-coding gene located on chromosome 2.

The FARSB gene encodes a highly conserved enzyme, phenylalanyl-tRNA synthetase beta chain, which is part of the aminoacyl-tRNA synthetase class IIc subfamily. It forms a tetramer with two catalytic alpha subunits, encoded by FARSA, responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA in the presence of ATP. This gene has a pseudogene located on chromosome 10.

FARSB is also known as FARSLB, FRSB, HSPC173, NEDBLLA, PheHB, PheRS, RILDBC, RILDBC1, RJBS.

Associated Diseases


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