F7 : coagulation factor VII
Description
The F7 gene provides instructions for making a protein called coagulation factor VII, a crucial component of the coagulation cascade. This cascade is a complex series of steps that stops bleeding by forming a blood clot. Factor VII activates other clotting factors, ultimately leading to the formation of a fibrin mesh that traps blood cells and seals the wound. Mutations in the F7 gene can disrupt this process, resulting in various bleeding disorders.
Associated Diseases
Did you know?
Factor VII is the only vitamin K-dependent clotting factor that is not synthesized in the liver.
