F13B : coagulation factor XIII B chain
Description
The F13B gene provides instructions for making a protein called fibrin-stabilizing factor B, a vital component of the blood clotting cascade. This protein works in tandem with fibrin-stabilizing factor A (encoded by the F13A gene) to strengthen blood clots, preventing excessive bleeding. Mutations in the F13B gene can lead to a rare bleeding disorder known as fibrin-stabilizing factor deficiency, causing prolonged bleeding episodes. This gene also plays a role in wound healing and inflammation, highlighting its critical role in maintaining the body‘s defense mechanisms.
Associated Diseases
Did you know?
F13B gene is also known as the coagulation factor XIII subunit B gene.
