EPS8

Description

The EPS8 gene, located on chromosome 11, encodes a protein called EPS8, a crucial player in cell signaling and migration. EPS8 interacts with a variety of proteins, including the epidermal growth factor receptor (EGFR) and the adaptor protein Grb2, to regulate downstream signaling pathways involved in cell growth, proliferation, and movement. EPS8's role in these fundamental cellular processes makes it a vital target for understanding and potentially treating diseases associated with abnormal cell growth and migration.

Associated Diseases

• Cancer (particularly breast and colorectal cancer)
• Neurological disorders (such as Alzheimer's disease)
• Developmental abnormalities

Did you know?

EPS8 is named after its ability to bind to the epidermal growth factor receptor (EGFR), a key player in cell growth and proliferation.