EGR1
Description
The EGR1 gene, also known as early growth response protein 1, encodes a zinc finger transcription factor that plays a crucial role in cellular responses to a wide range of stimuli, including growth factors, stress, and inflammation. EGR1 acts as a molecular switch, regulating the expression of numerous genes involved in cell proliferation, differentiation, apoptosis, and immune response. Its expression is tightly controlled and its dysregulation is linked to various diseases.
Associated Diseases
- Cancer (e.g., breast cancer, prostate cancer)
- Cardiovascular disease
- Neurological disorders (e.g., Alzheimer‘s disease, stroke)
- Immune disorders (e.g., rheumatoid arthritis)
- Inflammatory bowel disease
Did you know?
EGR1 is a rapid response gene, meaning its expression can be dramatically increased within minutes after exposure to stimuli.
