DMP1
Description
DMP1 (dentin matrix protein 1) is a crucial non-collagenous protein essential for the mineralization and structural integrity of bones and teeth. It plays a multifaceted role in orchestrating the intricate processes of bone formation, including osteoblast differentiation, mineralization, and matrix maturation. DMP1 exerts its influence by interacting with other proteins, such as bone morphogenetic proteins (BMPs), and regulating their signaling pathways. The gene encoding DMP1, located on chromosome 4, undergoes complex splicing events, resulting in multiple isoforms with distinct functions.
Associated Diseases
Did you know?
DMP1 is one of the most highly phosphorylated proteins in the human body, with over 100 potential phosphorylation sites.
