DCHS1
Description
DCHS1 (Dachsous 1) is a transmembrane protein involved in cell-cell adhesion and tissue morphogenesis. It plays a crucial role in regulating cell fate, cell polarity, and tissue patterning during development. DCHS1 belongs to the Dachsous cadherin family, which is characterized by a unique structure consisting of multiple cadherin domains, a transmembrane domain, and a cytoplasmic tail. These cadherin domains mediate interactions between neighboring cells, contributing to the formation of cohesive tissues. DCHS1 is highly conserved across species, highlighting its fundamental importance in cellular processes.
Associated Diseases
Did you know?
DCHS1 mutations have been linked to a rare genetic disorder called Van der Woude syndrome, which is characterized by cleft lip and palate.
