DAG1

Description

DAG1 (Disabled-1) is a transmembrane protein that plays a crucial role in cell-cell adhesion and signaling pathways. It belongs to the immunoglobulin superfamily and is expressed in various tissues, including the nervous system, heart, and skeletal muscle. DAG1 interacts with a diverse array of proteins, mediating cell adhesion, neuronal migration, and signal transduction. Its malfunction can lead to various developmental and neurological disorders.

Associated Diseases

• Congenital Muscular Dystrophy 1A (CMD1A)
• Spinal Muscular Atrophy (SMA)
• Autism Spectrum Disorder (ASD)
• Schizophrenia

Did you know?

DAG1 is a fascinating example of how a single gene can contribute to multiple developmental and neurological disorders, highlighting its importance in cell adhesion and signaling.