CYP2C8
Description
The CYP2C8 gene provides instructions for making an enzyme called cytochrome P450 2C8, a crucial component of the liver's drug-metabolizing system. This enzyme breaks down various medications, including statins, anti-diabetic drugs, and certain anti-cancer medications. Variations in the CYP2C8 gene can affect how quickly these drugs are processed, leading to differences in drug efficacy and potential side effects. Understanding CYP2C8's role is vital for personalized medicine approaches, aiming to optimize drug therapy based on individual genetic profiles.
Associated Diseases
Did you know?
CYP2C8 is highly polymorphic, meaning it exhibits significant variation across individuals, leading to diverse drug responses.