CRPPA : CDP-L-ribitol pyrophosphorylase A
Description
The CRPPA gene, located on chromosome 17, encodes for the calcium-dependent phospholipid-binding protein, also known as C2 domain-containing protein A. This protein plays a crucial role in cell signaling pathways by binding to calcium ions and phospholipids, facilitating interactions between proteins and membranes. Its involvement in various cellular processes, including vesicle trafficking, cell adhesion, and apoptosis, makes it a vital component of maintaining cellular homeostasis. The gene‘s dysregulation can lead to a range of diseases, highlighting its significance in health and disease.
Associated Diseases
- Cancer (e.g., breast cancer, lung cancer)
- Neurological Disorders (e.g., Alzheimer‘s disease, Parkinson‘s disease)
- Cardiovascular Diseases (e.g., heart failure, atherosclerosis)
- Inflammatory Diseases (e.g., rheumatoid arthritis, inflammatory bowel disease)
Did you know?
CRPPA gene expression is often altered in various cancer cells, indicating its potential as a biomarker for cancer diagnosis and prognosis.
