COLEC10 : collectin subfamily member 10
Description
The COLEC10 (collectin subfamily member 10) is a protein-coding gene located on chromosome 8.
The COLEC10 gene provides instructions for making a protein called collectin liver 1 (CL-L1). This protein is involved in the lectin complement pathway, which helps guide cell movement (migration) during development before birth to form the organs and systems of the body. This pathway is particularly important in directing the migration of neural crest cells, which give rise to tissues including those in the face and skull, hormone-producing glands (endocrine glands), and parts of the nervous system. After birth, the lectin complement pathway is involved in the immune system.
Collectin-10 binds to various sugars, including galactose, mannose, fucose, N-acetylglucosamine, and N-acetylgalactosamine. It acts as a chemoattractant and is likely involved in regulating cell migration. (PubMed:10224141, PubMed:28301481)
COLEC10 is also known as 3MC3, CL-10, CL-34, CLL1.
