COG8
Description
The COG8 (component of oligomeric golgi complex 8) is a protein-coding gene located on chromosome 16.
COG8 (Conserved oligomeric Golgi complex subunit 8) is a protein encoded by the COG8 gene in humans. The Golgi apparatus is a vital organelle involved in intracellular transport and glycoprotein modification. COG8 is part of the conserved oligomeric Golgi complex (COG), which is essential for the structure and function of the Golgi. The COG complex is composed of eight different subunits and is crucial for normal Golgi morphology and localization. It plays a role in various cellular processes, including glycosylation reactions and vesicular transport. Defects in COG8 can lead to congenital disorders of glycosylation (CDG), a group of genetic disorders affecting the glycosylation process.
COG8 is essential for the proper functioning of the Golgi apparatus.
COG8 is also known as CDG2H, DOR1.
