CHRNG : cholinergic receptor nicotinic gamma subunit
Description
The CHRNA5 gene encodes the alpha-5 subunit of the nicotinic acetylcholine receptor (nAChR), a protein crucial for neurotransmission in the central nervous system. This receptor is involved in various functions, including learning, memory, and reward pathways. Variations in the CHRNA5 gene have been linked to nicotine addiction, as well as other neurological conditions like Alzheimer‘s disease and Parkinson‘s disease.
Associated Diseases
- Nicotine addiction
- Alzheimer‘s disease
- Parkinson‘s disease
- Schizophrenia
- Attention-deficit/hyperactivity disorder (ADHD)
Did you know?
Mutations in the CHRNA5 gene have been associated with an increased risk of developing nicotine addiction, particularly in individuals with a family history of the disorder.
