CARD10
Description
CARD10, also known as caspase recruitment domain-containing protein 10, is a crucial component of the innate immune system, playing a vital role in the activation of NF-κB signaling pathway. This pathway is responsible for regulating the expression of genes involved in inflammation and immune responses. CARD10 functions as an adapter protein, bridging the interaction between various signaling molecules and ultimately leading to the activation of NF-κB. This activation triggers the production of cytokines, chemokines, and other inflammatory mediators, which are essential for mounting an effective immune response against pathogens. Dysregulation of CARD10 activity can contribute to various inflammatory and autoimmune diseases, highlighting its importance in maintaining immune homeostasis.
Associated Diseases
- Autoinflammatory diseases
- Inflammatory bowel disease (IBD)
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Cancer
Did you know?
CARD10 is involved in the activation of NF-κB signaling pathway, which is also known as the "master regulator" of inflammation.
