CA8

Description

The CA8 gene encodes for carbonic anhydrase VIII, an enzyme that plays a crucial role in regulating carbon dioxide (CO2) levels in the body. Carbonic anhydrases are a family of zinc metalloenzymes that catalyze the reversible hydration of CO2 to bicarbonate (HCO3-) and protons (H+). This reaction is essential for a variety of physiological processes, including respiration, pH regulation, and electrolyte balance. CA8 is particularly important in the brain, where it is thought to contribute to neuronal function and neuroprotection.

Associated Diseases

• Hypoxia-ischemia (Brain Damage)
• Cancer (e.g., breast, prostate, and lung)
• Glaucoma
• Obesity
• Diabetes

Did you know?

CA8 is unique among the carbonic anhydrases in that it is primarily found in the brain, specifically in neurons and glial cells.