C1QBP
Description
C1QBP, also known as gC1qR, is a protein that plays a crucial role in the innate immune system. It acts as a bridge between the complement system and various cellular processes, influencing immune cell activation, inflammation, and tissue repair. C1QBP binds to the C1q component of the complement pathway, facilitating its interaction with cell surface receptors. This interaction triggers downstream signaling cascades that modulate immune responses. C1QBP is also involved in other cellular processes, including apoptosis, autophagy, and cell adhesion. Dysregulation of C1QBP expression or function has been implicated in a variety of diseases, highlighting its importance in maintaining immune homeostasis.
Associated Diseases
- Systemic Lupus Erythematosus (SLE)
- Rheumatoid Arthritis (RA)
- Multiple Sclerosis (MS)
- Cancer
- Neurodegenerative Diseases
Did you know?
C1QBP is a highly conserved protein, suggesting its critical role in immune function across different species.