BRF1
Description
The BRF1 gene encodes a protein that plays a crucial role in the transcription of genes involved in immune responses. This protein, known as BRF1, acts as a transcription factor, binding to specific DNA sequences and regulating the expression of various immune-related genes. It is essential for the proper functioning of immune cells, including T lymphocytes and macrophages, which are critical for fighting infections and maintaining immune homeostasis.
Associated Diseases
- Autoimmune diseases (e.g., lupus, rheumatoid arthritis)
- Immunodeficiency disorders (e.g., common variable immunodeficiency)
- Infectious diseases (e.g., susceptibility to recurrent infections)
- Cancer (e.g., lymphoma, leukemia)
Did you know?
Mutations in the BRF1 gene are associated with increased susceptibility to certain viral infections, highlighting its importance in antiviral immunity.
