BRAT1
Description
BRAT1 (BRCA1 Associated Transcript 1) is a gene that plays a critical role in DNA repair, specifically homologous recombination. It interacts with BRCA1, another crucial gene involved in DNA damage response, and together they participate in maintaining genomic stability. BRAT1 is expressed in various tissues, including breast, ovary, and prostate, and its dysfunction can lead to an increased risk of cancer development. BRAT1‘s role in DNA repair is essential for preventing mutations and ensuring proper cell division, making it a significant player in cancer prevention.
Associated Diseases
Did you know?
BRAT1 was initially discovered as a transcript associated with the BRCA1 gene, highlighting the close relationship between these two genes in DNA repair processes.