ANTXR2 : ANTXR cell adhesion molecule 2
Description
The ANTXR2 gene, also known as the annexin A2 receptor, plays a crucial role in various cellular functions. It encodes a protein that serves as a receptor for annexin A2, a protein involved in membrane trafficking, signal transduction, and cell adhesion. ANTXR2 is expressed in various tissues, including the brain, heart, and lungs. It is implicated in diverse biological processes, such as inflammation, angiogenesis, and tumor growth.
Associated Diseases
- Cancer (particularly breast, lung, and colorectal cancers)
- Alzheimer‘s disease
- Neurodegenerative disorders
- Cardiovascular diseases
- Inflammatory bowel disease
- Autoimmune disorders
Did you know?
ANTXR2 has been shown to interact with the amyloid-beta protein, which is a key player in the development of Alzheimer‘s disease.