ALDOB : aldolase, fructose-bisphosphate B
Description
The ALDOB gene provides instructions for making the enzyme aldolase B, a crucial component in the breakdown of fructose. Located on chromosome 9, ALDOB plays a vital role in converting fructose-1-phosphate to glyceraldehyde and dihydroxyacetone phosphate. This process is essential for energy production and proper liver function. A deficiency in aldolase B leads to the accumulation of fructose-1-phosphate, resulting in various metabolic complications.
Associated Diseases
Did you know?
HFI is a rare genetic disorder, affecting approximately 1 in 20,000 individuals worldwide.
