ALDH4A1 : aldehyde dehydrogenase 4 family member A1
Description
The ALDH4A1 gene encodes the enzyme aldehyde dehydrogenase 4A1, a vital component of cellular metabolism, primarily in the liver. It plays a crucial role in detoxifying harmful aldehydes, byproducts of alcohol and other metabolic processes, into harmless carboxylic acids. ALDH4A1 is particularly important in the breakdown of retinoic acid, a crucial molecule for vision and cell growth. Dysfunction or deficiency of this enzyme can lead to a buildup of toxic aldehydes, potentially contributing to various diseases.
Associated Diseases
Did you know?
Mutations in the ALDH4A1 gene are associated with an increased risk of developing certain types of cancer, particularly those related to alcohol consumption.
