ALDH18A1 : aldehyde dehydrogenase 18 family member A1


Description

The ALDH18A1 gene encodes the enzyme 18-kDa mitochondrial aldehyde dehydrogenase (ALDH18A1). This enzyme plays a crucial role in lipid metabolism, particularly in the degradation of branched-chain fatty acids (BCFAs). BCFAs are essential components of cell membranes and have various metabolic functions. ALDH18A1 catalyzes the oxidation of branched-chain fatty acyl-CoA to their corresponding branched-chain fatty acids, a crucial step in their breakdown. This process is essential for maintaining energy homeostasis and proper cellular function.

Associated Diseases

Did you know?

ALDH18A1 is also involved in the metabolism of certain drugs and toxins, highlighting its broader role in detoxification processes.


Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.