AKR1C2

Description

The AKR1C2 gene encodes for the enzyme aldo-keto reductase 1C2, a crucial component in the metabolism of steroid hormones. This enzyme plays a significant role in the detoxification of harmful substances, and its activity is tightly regulated within various tissues. Dysregulation of AKR1C2 expression or function has been linked to several diseases, highlighting its importance in maintaining health.

Associated Diseases

• Breast Cancer
• Prostate Cancer
• Ovarian Cancer
• Endometrial Cancer
• Lung Cancer
• Diabetes
• Obesity
• Cardiovascular Disease

Did you know?

AKR1C2 is a highly polymorphic gene, meaning it exists in multiple variations within the population. These variations can influence enzyme activity and contribute to individual differences in drug metabolism and disease susceptibility.