AK1
Description
The AK1 gene, also known as adenylate kinase 1, plays a crucial role in cellular energy production and signaling pathways. It encodes an enzyme that catalyzes the reversible interconversion of adenine nucleotides, specifically ADP and AMP. This process is essential for maintaining energy homeostasis and regulating various cellular functions, including growth, differentiation, and apoptosis. AK1 is particularly abundant in tissues with high energy demands, such as skeletal muscle, heart, and brain. Its expression is tightly regulated, and mutations in the AK1 gene can lead to a range of inherited metabolic disorders.
Associated Diseases
Did you know?
AK1 activity is significantly elevated in cancer cells, suggesting its potential role in tumor growth and proliferation.
